Celiac Disease and the gut studied with MRI
05/21/2025
Celiac disease is a chronic disease caused in genetically predisposed individuals by an autoimmune reaction to the intake of gluten which damages the intestinal mucosa, causing symptoms such as abdominal pain, bloating, diarrhea or constipation, and weight loss.
The disease is kept under control with a strict gluten-free diet which manages symptoms and promotes recovery of intestinal mucosa function. In order to further investigate the effects of the disease and the gluten-free diet on the gut, a team of researchers from the University of Nottingham (UK) used magnetic resonance imaging (MRI) to compare the function of the gut of celiac subjects before and after the gluten-free diet compared to healthy individuals.
The most interesting data that have emerged from this new research concern changes in the intestinal microbiota in celiac subjects, before and after the gluten-free diet.