News

The objective of a recent study was to evaluate the structural and inflammatory features of NCWS compared to controls and celiac disease with milder enteropathy, since the histological changes induced by gluten in the duodenal mucosa of patients with NCWS is not well defined.

While the worldwide prevalence of celiac disease is 1%, its prevalence rises significantly among patients with concurrent type 1 diabetes mellitus (T1DM). Both celiac disease and T1DM are autoimmune disorders and require careful and lifelong management to avoid long-term health consequences.

While categorized as a digestive disorder, Irritable Bowel Syndrome (IBS) affects far more than the digestive tract. The most common symptoms of IBS include abdominal pain, bloating, constipation, and diarrhea, all of which not only cause physical discomfort, but also have a significant impact on a quality of life and mental health.

FODMAP (fermentable oligosaccharides, monosaccharides, monosaccharides, and polyols) reduction may be clinically beneficial in irritable bowel syndrome (IBS), but the mechanism is not fully understood.

People with celiac disease often experience a long journey before being diagnosed with celiac disease. Delays in diagnosis prevent treatment of the symptoms and leads to significant quality of life disruption. A recent survey of people with celiac disease and their relatives examined the experiences that patients had on their way to diagnosis and provided insights as to how their situation could have been improved.

While strides have been made in recent years, accurate and timely diagnosis of celiac disease remains a challenge. Diagnosis is a multi-step process that includes clinical history, serology, histology, and symptom improvement and antibody response following transition to a gluten-free diet.

While a balanced diet remains a cornerstone in promoting digestive function, current understanding of the gut-brain axis highlights the important role sleep, exercise, stress, and other psychological factors play in maintaining GI homeostasis.

Recent studies seek to assess how probiotic, prebiotic, fermented foods, polyphenols and foods with resistant starch may support increased abundance and resilience of beneficial (commensal) microbes in patients with dysbiosis, though evidence to support their use remains limited to date.

A large focus in the treatment of IBS and other gastrointestinal conditions is regulation of intestinal permeability and promotion of intestinal barrier function.