Prevalence of non-celiac gluten sensitivity

  1. Dr. Schär Institute
  2. Prevalence of non-celiac gluten sensitivity

Estimated prevalence of non-celiac gluten sensitivity (NCGS) varies between 1% and 13% of the population, and as such may be higher than the prevalence of celiac disease. Unreported cases are likely to be at a similarly high level to celiac disease [1].

Research indicates that NCGS is probably more prevalent than celiac disease. Until now, however, there has been a lack of extensive epidemiological studies to verify estimated prevalence of this condition. Clinic data from the Center for Celiac Research, University of Maryland, showed that 6% of the 9,000 patients treated there between 2004-2010 met the criteria for NCGS and complained of corresponding symptoms, without having celiac disease or wheat allergy [2]. In a recent UK study 13% of a general population sample reported symptoms attributed to gluten [3]. 

References

  1. Aziz I, Hadjivassiliou M, Sanders DS.The spectrum of noncoeliac gluten sensitivity. Nat Rev Gastroenterol Hepatol. 2015 Epub ahead of print
  2. Sapone A, Bai JC, Ciacci C et al. Spectrum of gluten-related disorders: consensus on new nomenclature and classification. BMC Med 2012; 10: 13.
  3. Aziz, I. et al. A UK study assessing the population prevalence of self-reported gluten sensitivity and referral characteristics to secondary care. Eur. J. Gastroenterol. Hepatol. 26, 33–39 (2014).